Composition
Florfenicol 300 mg

Indications
Diseases caused by florfenicol susceptible bacteria.

• Cattle
  Treatment of respiratory tract infections due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni.
• Pigs
  Treatment of acute outbreaks of swine respiratory disease caused by strains of Actinobacillus pleuropneumoniae and Pasteurella multocida susceptible to florfenicol.

Contra-indications
Do not use in adult bulls or boars intended for breeding purposes.
Do not use in cattle producing milk for human consumption.
Do not administer in cases of hypersensitivity to the active ingredient or any of the excipients.

Special precautions
Special precautions for use in animals
Wipe the stopper before removing each dose. Use a dry, sterile needle and syringe. Do not use in piglets of less than 2 kg.
Under field conditions, approximately 30% of treated pigs presented with pyrexia (40°C) associated with either moderate depression or moderate dyspnoea a week or more after administration of the second dose. The product should be used in conjunction with susceptibility testing and take into account official and local antimicrobial policies.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Care should be taken when handling the product to avoid accidental self-injection. In case of accidental self-injection, seek medical advice, and show the package leaflet or the label to the physician. People with known hypersensitivity to the components of the formulation should avoid contact with the product. Wash hands after handling the product.

Posology
Intramuscular use.
The injection should be given in the neck.

• Cattle
  20 mg florfenicol per kg bodyweight, i.e. 1 ml of solution per 15 kg bodyweight, twice 48 hours apart.
• Pigs
  15 mg florfenicol per kg bodyweight, i.e. 1 ml of solution per 20 kg bodyweight, twice 48 hours apart.

The dose volume given at any one injection site should not exceed 10 ml in cattle and 3 ml in pigs. To ensure a correct dosage body weight should be determined as accurately as possible to avoid underdosing.
It is recommended to treat animals in the early stages of disease and to evaluate the response to treatment within 48 hours after the second injection. If clinical signs of respiratory disease persist 48 hours after the last injection, treatment should be changed using another formulation or another antibiotic and continued until clinical signs have resolved.

Withdrawal period

• Cattle
  Meat and offal: 37 days
  Milk: Not permitted for use in lactating animals producing milk for human consumption.
• Pigs
  Meat and offal: 18 days

Storage
This veterinary medicinal product does not require any special storage conditions.

Packaging
Material of the primary container
Colourless glass vial type II (20 – 50 – 100 – 250 - 500 ml).
Translucent multi-layer plastic vials (50 – 100 – 250 – 500 ml).
Chlorobutyl stopper type II.

Pack size
Box containing 20, 50, 100, 250 or 500 ml vials.
Not all pack sizes may be marketed.

_{From one country to another, product lines are adapted to local demand and regulatory requirements. For further information, please take a look at the CEVA Santé Animale site for your country. Warning: the information provided on the products depends on national registrations. Access to technical information is restricted to authorised persons.}