Qualitative and quantitative composition Active ingredients and excipients with known effects:
One ml contains: - Active substances: Benzylpenicillin (as procaine) 114.0 mg Dihydrostreptomycin (as sulphate) ..... 200.0 mg - Excipients: Sodium hydroxyl-4-benzoate methyl ester 1.4 mg Sodium hydroxymethylsulphinate ..... 4.0 mg
Procaïne (hydrochloride salt) 17.3 mg
Suspension for injection.
Cattle, sheep, goats, pigs, dogs and cats.
Indications for use, specifying the target species:
In cattle, sheep, goats, pigs, dogs and cats: - treatment of generalized infections of the young and adult, pneumonia and pleuropneumonia, postpartum infections, urinary infections, infected wounds (such as interdigitated panaris, etc.), abscesses (such as omphalophlebitis. ..), and postoperative infections due to penicillin and dihydrostreptomycin sensitive germs.
Do not administer in case of known allergy to penicillins or local anesthetics. Do not administer to rabbits, guinea pigs, hamsters or gerbils.
Special warnings for each target species:
Special precautions for use in animals:
Improper use of the product may increase the prevalence of penicillin or dihydrostreptomycin resistant bacteria.
In patients with renal or dehydrated insufficiency, the dosage should be evaluated carefully.
Drug and other interactions:
- Cattle, sheep, goats, pigs
11.4 to 17.1 mg of benzylpenicillin and 20 to 30 mg of dihydrostreptomycin per kg of live weight per day intramuscularly or subcutaneously for 3 to 5 days, ie 1 to 1.5 ml of suspension per 10 kg of live weight intramuscularly or subcutaneously (corresponding to 10 ml suspension per 100 kg liveweight in adult bovine, ovine, caprine and porcine animals and 1.50 ml per 10 kg live-weight in calves, lambs , goats and piglets).
- Dogs, cats
22.8 mg of benzylpenicillin and 40 mg of dihydrostreptomycin per kg of body weight per day intramuscularly or subcutaneously for 3 to 5 days or 2 ml of suspension per 10 kg of body weight intramuscularly or subcutaneously
Shake the bottle well to homogenize the suspension before use.
Intramuscular or subcutaneous routes.
Overdose (symptoms, emergency procedures, antidotes):
In massive overdosage, dihydrostreptomycin can induce neuromuscular blockage, especially in cats, resulting in flaccid paralysis and cardiorespiratory depression, which can be controlled by calcium intravenous administration.
Meat and offal:
- bovine, ovine, caprine and swine: 30 days.
- cattle, goats: 7 days.
- sheep: 6 days.