Infection of the small intestine by type C, D and A strains of C perfringens causes a highly fatal, necrohemorrhagic enteritis. It most commonly affects piglets 1–5 days old but may be seen in pigs up to 3 wk old. Vaccination of gestating sows at 6 and 3 wk before parturition with type C, D and A bacterin-toxoid.
Coglamune®, confers passive lactogenic immunity to subsequent litters, if piglets consume colostrum soon after birth. Once immunized with two doses of Coglamune®, sows should receive one dose 3 weeks before each subsequent farrowing.
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