HYOGEN® EDITION 1
In an experimental trial performed in the University of Ghent and published during ESPHM congress in 2016, a double M. hyo strain challenge tried to stimulate the situation of multiple infections which can occur in the farm condition.
Vaccination with Hyogen® modified the immune response in a way that the local antibody response in the initial phase post infection was stronger than the positive control and the production of the pro-inflammatory cytokines was milder than the positive control, yet still higher than the negative control. Such “more appropriate” immune response may be a decisive factor of protection with the immune system activated enough to struggle with the germ (lower M. hyo qPCR) yet not too much to stimulate chronic inflammatory processes and development of extensive chronic pneumonia...
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