Coglapix Edition 1
A field trial performed with Coglapix® in The Netherlands is described in a farm presenting Actinobacillus pleuropneumoniae infection.
Using a veterinary application, “VetApp”, which has been developed to follow-up the health status on pig farms during the monthly farm visits, a reduction of the coughing index has been associated with a drop of mortality by approximately 50% and the antibiotic use was reduced to almost zero after the introduction of the vaccine.
Coglapix Edition 2
The distribution of various serotypes of Actinobacillus pleuropneumoniae differs substantially among countries.
The presence of various serotypes in a farm as well as in a given area doesn’t stay stable, but evolves over the time.
Serotype 8 is the most prevalent in the UK and was isolated also in other countries as highly virulent. In an experimental challenge trial, Coglapix® documented high efficacy against the serotype 8 of A. pleuropneumoniae.
There was the lowest rate of clinical symptoms and no mortality in pigs vaccinated with Coglapix®.
Coglapix Edition 3
Lung scoring together with serological profiling of the herd is a useful approach to assess prevalence and severity of some important respiratory pathogens and determine a most efficient vaccination program.
Dr Andrea Luppi from Izsler Institute is sharing the main conclusion of a large epidemiological study performed in Italy. This study demonstrates that:
the Enzootic Pneumonia (EP)-like lesions average values show significant associations with the intra herd seroprevalence for M.hyo at 18 weeks of age, confirming a good correlation between the EP like lesions recorded at the slaughter house and previous M.hyo infection.
Dorso-caudal pleurisy average value and Actinobacilluspleuropneumonaie index (API) are significantly associated to A.p herd seroprevalence.
These evaluations confirm once again the importance of the scoring of the lungs at the slaughterhouse, in order to discover pleural lesions due to sub-clinical cases and bronchopneumonia lesions, otherwise often under estimated…
Coglapix Edition 4
Professor Marcelo Gottschalk from the University of Montreal is sharing the main available tools to help diagnosing the porcine pleuropneumonia disease in its different forms.
The diagnosis of the subclinical forms of porcine pleuropneumonia is complicated. Serology against all serotypes of App (based on Apx IV toxin-based ELISA) can be performed. First, samples at the slaughter house can be taken (between 25 and 30 serum samples).
In presence of clinical signs, the identification of the serotype after isolation, serological tests or more specific tests (PCR) can be performed to indicate or not the presence of a highly virulent serotype, and help control the spread of infection in the herd.
Moreover, Pr Gottschalk explains that it would be extremely dangerous to establish a correlation between the antibodies detected by commercial kits and protection of vaccinated animals.
Coglapix Edition 5
Outcome from a respiratory diseases survey in Germany
Matthias eddicks PhD in vet medicine from the ludwig-Maximilians-university Munich highlighted throw this study the Ap serotype distribution and difference in the regional epidemiological situation, he explained also how lung scoring combined to serology could be a relevent diagnostic for monitoring respiratory pathogens both Ap & M.hyo in the farms.
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