Coglapix® Editions

Inactivated vaccine against swine pleuropeumonia caused by Actinobacillus pleuropeumoniae

Coglapix Edition 1

A field trial performed with Coglapix® in The Netherlands is described in a farm presenting Actinobacillus pleuropneumoniae infection.

Using a veterinary application, “VetApp”, which has been developed to follow-up the health status on pig farms during the monthly farm visits, a reduction of the coughing index has been associated with a drop of mortality by approximately 50% and the antibiotic use was reduced to almost zero after the introduction of the vaccine.

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Coglapix Edition 2

The distribution of various serotypes of Actinobacillus pleuropneumoniae differs substantially among countries.

The presence of various serotypes in a farm as well as in a given area doesn’t stay stable, but evolves over the time.

Serotype 8 is the most prevalent in the UK and was isolated also in other countries as highly virulent. In an experimental challenge trial, Coglapix® documented high efficacy against the serotype 8 of A. pleuropneumoniae.

There was the lowest rate of clinical symptoms and no mortality in pigs vaccinated with Coglapix®.

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Coglapix Edition 3

Lung scoring together with serological profiling of the herd is a useful approach to assess prevalence and severity of some important respiratory pathogens and determine a most efficient vaccination program.

Dr Andrea Luppi from Izsler Institute is sharing the main conclusion of a large epidemiological study performed in Italy. This study demonstrates that:

 the Enzootic Pneumonia (EP)-like lesions average values show significant associations with the intra herd seroprevalence for M.hyo at 18 weeks of age, confirming a good correlation between the EP like lesions recorded at the slaughter house and previous M.hyo infection.

 Dorso-caudal pleurisy average value and Actinobacilluspleuropneumonaie index (API) are significantly associated to A.p herd seroprevalence.

 These evaluations confirm once again the importance of the scoring of the lungs at the slaughterhouse, in order to discover pleural lesions due to sub-clinical cases and bronchopneumonia lesions, otherwise often under estimated…

To Read More please , click to download the complete Study 

Coglapix Edition 4

Professor Marcelo Gottschalk from the University of Montreal is sharing the main available tools to help diagnosing the porcine pleuropneumonia disease in its different forms.

 The diagnosis of the subclinical forms of porcine pleuropneumonia is complicated. Serology against all serotypes of App (based on Apx IV toxin-based ELISA) can be performed. First, samples at the slaughter house can be taken (between 25 and 30 serum samples).
 In presence of clinical signs, the identification of the serotype after isolation, serological tests or more specific tests (PCR) can be performed to indicate or not the presence of a highly virulent serotype, and help control the spread of infection in the herd.
 Moreover, Pr Gottschalk explains that it would be extremely dangerous to establish a correlation between the antibodies detected by commercial kits and protection of vaccinated animals. 

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Coglapix Edition 5

Outcome from a respiratory diseases survey in Germany

Matthias eddicks PhD in vet medicine from the ludwig-Maximilians-university Munich highlighted throw this study the Ap serotype distribution and difference in the regional epidemiological situation, he explained also how lung scoring combined to serology could be a relevent diagnostic for monitoring respiratory pathogens both Ap & M.hyo in the farms.

To Read More please , click to download the complete Study 

From one country to another, product lines are adapted to local demand and regulatory requirements. For further information, please take a look at the CEVA Santé Animale site for your country. Warning: the information provided on the products depends on national registrations. Access to technical information is restricted to authorised persons.

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